Smoking, Alcohol and (O)esophageal Cancer

Usage

data(esoph)

Format

data frame with records for 88 age/alcohol/tobacco combinations.
[,1] "agegp" Age group 1 25-34 years
2 35-44
3 45-54
4 55-64
5 65-74
6 75+
[,2] "alcgp" Alcohol consumption 1 0-39 gm/day
2 40-79
3 80-119
4 120+
[,3] "tobgp" Tobacco consumption 1 0- 9 gm/day
2 10-19
3 20-29
4 30+
[,4] "ncases" Number of cases
[,5] "ncontrols" Number of subjects

Description

Data from a case-control study of (o)esophageal cancer in Ile-et-Vilaine, France.

Author(s)

Thomas Lumley

Source

Breslow and Day (1980). "Statistical Methods in Cancer Research. 1: The Analysis of Case-control studies"; IARC Lyon.

Examples

data(esoph)
summary(esoph)
## effects of alcohol, tobacco and interaction, age-adjusted
model1 <- glm(cbind(ncases, ncontrols) ~ agegp + tobgp * alcgp,
              data = esoph, family = binomial())
anova(model1)
## Try a linear effect of alcohol and tobacco
model2 <- glm(cbind(ncases, ncontrols) ~ agegp + codes(tobgp) + codes(alcgp),
              data = esoph, family = binomial())
summary(model2)

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